Identification of a novel RNA aptamer that selectively targets breast cancer exosomes
Academic Article
Publication Date:
2021
abstract:
Extracellular vesicles are important biomarkers and therapeutic targets for breast cancer (BC). However, specific tools for their recognition are lacking. Condorelli and colleagues describe the finding of a high-affinity aptamer (ex-50.T) able to specifically target BC exosomes acting as a promising diagnostic and therapeutic tool.
Iris type:
01.01 Articolo in rivista
Keywords:
aptamers; blood; breast cancer; early diagnosis; exosomes; identification; liquid biopsy; SELEX; serum markers; therapy
List of contributors:
DE FRANCISCIS, Vittorio; Condorelli, Gerolama; Rotoli, Deborah; Catuogno, Silvia; Esposito, CARLA LUCIA; Quintavalle, Cristina
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