First time reported 6,8 FQs photoogenerated triplet heteroarylcation direct attack onto guanosine
Conference Poster
Publication Date:
2010
abstract:
The triplet aryl cation photochemically generated from fluoroquinolones bearing a fluoro atom in position 8 attacks guanine monophosphate (kr >109 M-1s-1) and forms covalent adducts. The reaction is a model for the implementation of oxygen-independent photochemotherapy
Iris type:
04.03 Poster in Atti di convegno
Keywords:
drug photochemistry
List of contributors: