Inclusion properties, metal ion coordination ability and analytical applications of trehalose-capped cyclodextrins. In: Proceedings of the IXth International Symposium on Cyclodextrins

A new capped derivative of beta-cyclodextrin was synthesized. The capping unit comprises a trehalose molecule, bridged to A and D primary groups of beta-cyclodextrin by nitrogen atoms. This compound, together to a similar compound previously synthesized, constitutes a new class of compounds, which we call hemispherodextrins. The synthesis, the characterization and the interaction with anthraquinone-2-sulfonic acid (ACS), as well as preliminary results on the interaction with proton and with copper(II) of this compound are reported and discussed.