Another extreme genome: how to live at pH 0

Many Archaea live under conditions that challenge the physico-chemical limits to life: low or high temperature, extremes of pH, elevated pressure and high salt concentration. A recent paper reports the genome sequence of another record-setting archaeon, Picrophilus torridus, that thrives at 65°C and pH 0. The genomic sequence provides several hints of the mechanisms used for adaptation to such hostile environment, but most secrets remain hidden and await further analysis to be disclosed.