Inhibition of Bacterial Carbonic Anhydrases as a Novel Approach to Escape Drug Resistance

Articolo
Data di Pubblicazione:
2017
Abstract:
Background: Clinically used antibiotics act through one of these four mechanisms: cell wall biosynthesis inhibition, inhibition of protein biosynthesis, interference with DNA and RNA synthesis and the folate pathway.
Tipologia CRIS:
01.01 Articolo in rivista
Keywords:
Carbonic anhydrase; Hydratase activity; Metalloenzymes; CA inhibitors; Pathogens; Selective inhibition; Antibacterial; Antiinfective; Sulfonamide; Anions; Inhibitor selectivity; Drug-design
Elenco autori:
Autori di Ateneo:
Link alla scheda completa:
https://iris.cnr.it/handle/20.500.14243/326240
Pubblicato in:
CURRENT TOPICS IN MEDICINAL CHEMISTRY (PRINT)
Journal