The influence of cyclic GMP on polypeptide synthesis in a cell-free system derived from wheat embryos

3?, 5? cyclic GMP stimulates polypeptide synthesis in a cell-free system derived from wheat embryos. The stimulatory effect is observed in presence either of crude or highly purified transfer factors. Attempts to elucidate the mechanism of cyclic GMP action indicated that this nucleotide influences the formation of the binary complex EF1-GTP and the conversion of the heavy form of EF1 into a lighter one. © 1974.