Mitochondrial Localization and Regulation of BRAF(V600E) in Thyroid Cancer: A Clinically Used RAF Inhibitor Is Unable to Block the Mitochondrial Activities of BRAF(V600E)
Academic Article
Publication Date:
2011
abstract:
Context: The oncogenic BRAF(V600E) mutation results in an active structural conformation characterized by greatly elevated ERK activity. However, additional cellular effects caused by subcellular action of BRAF(V600E) remain to be identified.
Iris type:
01.01 Articolo in rivista
List of contributors:
DE FALCO, Valentina
Published in: