Targeting endothelin-1 receptor/beta-arrestin1 network for the treatment of ovarian cancer
Academic Article
Publication Date:
2017
abstract:
Introduction: Endothelin-1 receptor (ET-1R)/beta-arrestin1 (beta-arr1) signaling is dysregulated in ovarian cancer. This signaling circuit enables cancer cells to engage several signaling and transcriptional networks that are pervasively intertwined, and represent a potential therapeutic target for developing novel agents for ovarian cancer treatment.
Iris type:
01.09 Rassegna della letteratura scientifica in rivista (Literature review)
Keywords:
Endothelin-1; beta-arrestin-1; ovarian cancer; ET-1 receptors; therapeutic target; ET-1 receptor antagonist
List of contributors:
Rosano', Laura
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