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Mathematical model of tumour cord growth along the source of nutrient

Academic Article
Publication Date:
2007
abstract:
A mathematical model of the tumour growth along a blood vessel is proposed. The model employs the mixture theory approach to describe a tissue which consists of cells, extracellular matrix and liquid. The growing tumour tissue is supposed to be surrounded by the host tissue. Tumours where complete oxydation of glucose prevails are considered. Special attention is paid to consistent description of oxygen consumption and growth processes based on the energy balance. A finite difference numerical method is proposed. The level set method is used to track an interface between the tissues. The simulations show localization of the tumour within a limited distance from the vessels and constant expansion velocity along the vessels.
Iris type:
01.01 Articolo in rivista
Keywords:
tumour growth; hypoxia; tumour cords; tumour-host interface; mathematical model; mixture theory; finite difference; level set method
List of contributors:
Tosin, Andrea
Handle:
https://iris.cnr.it/handle/20.500.14243/284542
Published in:
MATHEMATICAL MODELLING OF NATURAL PHENOMENA
Journal
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