A convenient catalytic procedure for the highly enantioselective aldol condensation of O-silyldienolates

In the presence of catalytic amount of chiral Ti(OiPr)(4)/BINOL (0.08 equiv.) the asymmetric aldol condensation of 6-methyl-4H-[1,3]-dioxin-4-one-derived silyloxydienes takes place in high yields and enantiomeric excesses with aromatic. heteroaromatic, Unsaturated and aliphatic aldehydes. Notable amplification of enantiomeric excesses have been obtained by using enantioenriched catalytic systems.