Natural Molecules as IKK a/b Inhibitors useful in the Treatment of Inflammation

Recently, there is a renewed interest in natural molecules used as protein kinase inhibitors with therapeutic potential. The possibility of obtaining these inhibitors from plants or vegetables, more safe compared to the synthetic one, represents a good target for the health demand. Natural compounds have been discovered to be effective in many disease treatments. Among these compounds are polyphenols and other natural molecules. They have been found to be able to interfere with many disease-related biochemical processes in vitro. They are capable of suppressing inflammation, tumor growth, bacterial infection, and virus infection. Thus, they have drawn great attention on the potential effects on disease prevention and treatment of carcinogenic, obesity, diabetic, and Alzheimer's diseases. In this review, the potential of natural molecules is elucidated in detail with an overview of recent researches and these studies would suggest that IKK inhibitors could be excellent new therapeutics.