Ethynylglycine synthon, a useful precursor for the synthesis of biologically active compounds: An update: Part I: Preparations of ethynylglycine synthon

The ethynylglycine synthon {(R)-2,2-dimethyl-3-(tert-butoxycarbonyl)-4-ethynyloxazolidine} is a chiral compound with valuable synthetic interest. An update on the different routes for its synthesis is reviewed and discussed.