New Cembranoids from the Hainan Soft Coral Sarcophyton glaucum

From the soft bodied coral Sarcophyton glaucum collected from the South China Sea two new cembranoids, (7R,8S)-dihydroxydeepoxy-ent-sarcophine (1) and secosarcophinolide (2), together with one known related compound, ent-sarcophine (3), were isolated. The Structures of the new compounds were determined by extensive analysis of their spectroscopic data and chemical correlation. e absolute configuration of 1 was determined by chemical correlation with 3 and by comparison of its optical rotation value with that of its corresponding enantiomer, (7S,8R)-dihydroxydeepoxysarcophine (5).