Terpenoids from North Adriatic sponge Spongia officinalis

Four C-21 furano terpenes, furospongin 2 and its three new isomen 1- 3, and three xalarane sesterterpenoids, 16-deacetyl-12-epi-scalarafuranacetate [5], deoxoscalarin acetate , and (-)-12-epideoxoxalarin, have been isolated from the sponge Spongia officinalis. The structural elucidation and cytotoxic activity of these compounds are reported