Witnessing the quantumness of a single system: From anticommutators to interference and discord

We introduce a method to witness the quantumness of a system. The method relies on the fact that the anticommutator of two classical states is always positive. By contrast, we show that there is always a nonpositive anticommutator due to any two quantum states. We notice that interference depends on the trace of the anticommutator of two states, and it is therefore operationally more suitable to detect quantumness by looking at anticommutators of states rather than their commutators.