Cellular Immune Response in Lynch Syndrome II on Gastrointestinal Biopsy

Immunoregulatory cell interactions between macrophages and T-cell subpopulations suggest the need for evaluation of the cellular immune response in gastrointestinal mucosa of asymptomatic subjects with Lynch Syndrome II. It was observed that macrophages pool coexists with T-cell subsets which had almost the same cellularity. However, an interesting movement of the immune cells distribution correlated to age were observed.