Identification of dipolar sources in tridimensional anisotropic cardiac muscle

A numerical method for the identification of intracardiac sources from epicardial and endocardial measured potentials is proposed (inverse problem in terms of sources). The method is based on transfer functions given by surface potentials generated by unit dipoles distributed on a regular grid inside anisotropic myocardium. In our model the anisotropic conductivity of myocardium takes into account the rotation of the fibers from epicardium to endocardium. The problem is typically ill posed and is solved by means of regularization methods.