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Photodynamic activity of thiophene-derived lysosome-specific dyes

Articolo
Data di Pubblicazione:
2016
Abstract:
The photodynamic activity occurring through the lysosome photo-damage is effective in terms of triggered synergic effects which can avoid chemo-resistance pathways. The potential photodynamic activity of two fluorescent lysosome-specific probes was studied providing their interaction with human serum albumin, demonstrating their in vitro generation of singlet oxygen and investigating the resulted photo-toxic effect in human cancer cells
Tipologia CRIS:
01.01 Articolo in rivista
Keywords:
HUMAN-SERUM-ALBUMIN; VIVO PHOTOSENSITIZING EFFICACY; CELL-DEATH; SINGLET OXYGEN; FLUORESCENT-PROBES; LIVING CELLS; THERAPY; APOPTOSIS; LOCALIZATION; ACTIVATION
Elenco autori:
Ciccarella, Giuseppe; Vergaro, Viviana
Autori di Ateneo:
VERGARO VIVIANA
Link alla scheda completa:
https://iris.cnr.it/handle/20.500.14243/422188
Pubblicato in:
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
Journal
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