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Cardiomyocyte troponin T immunoreactivity is modified by cross-linking resulting from intracellular calcium overload

Academic Article
Publication Date:
1996
abstract:
Background During myocardial ischemia, the increase in cytosolic Ca2+ promotes the activation of neutral proteases such as calpains. Since the troponin T subunit is a substrate for calpains, we investigated the effects of irreversible myocyte damage on troponin T immunoreactivity.
Iris type:
01.01 Articolo in rivista
Keywords:
calcium; reperfusion; troponin T; calpain; transglutaminase
List of contributors:
Menabo', Roberta
Authors of the University:
MENABO' ROBERTA
Handle:
https://iris.cnr.it/handle/20.500.14243/422151
Published in:
CIRCULATION (N.Y.N.Y.)
Journal
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