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Synthesis and anti HSV-1 evaluation of novel indole-3,4-diones

Academic Article
Publication Date:
2011
abstract:
A novel class of water soluble indole-3,4-diones has been synthesized and evaluated in vitro for antiviral activity against HSV-1. The results showed lack of cytotoxicity and significant antiviral activity. The cellular internalization efficiency and the antiherpetic effect were successfully increased by incorporation into nanoaggregates of an amphiphilic b-cyclodextrin.
Iris type:
01.01 Articolo in rivista
List of contributors:
Mazzaglia, Antonino
Authors of the University:
MAZZAGLIA ANTONINO
Handle:
https://iris.cnr.it/handle/20.500.14243/72698
Published in:
MEDCHEMCOMM (PRINT)
Journal
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