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Fat emulsions as diffusive reference standards for tissue simulating phantoms?

Articolo
Data di Pubblicazione:
2012
Abstract:
Intralipid 20% was recently suggested as a diffusive reference standard for tissue simulating phantoms. In this work, we extend previously obtained results to other fat emulsions, specifically Intralipid 10%, Intralipid 30%, Lipovenoes 10%, Lipovenoes 10% PhosphoLipid Reduced, Lipovenoes 20%, Lipofundin S 10%, and Lipofundin S 20%. Of particular importance for practical applications, our measurements carried out at a wavelength of 751 nm show the following features. First, these products show high stability and small batch-to-batch variations in their diffusive optical properties, similar to Intralipid 20%. Second, the absorption coefficient of Intralipid, Lipovenoes, and Lipofundin S are very similar and their measured values are within the experimental errors; moreover the reduced scattering coefficient of Intralipid 20%, Lipovenoes 20%, and Lipofundin S 20% are similar and their measured values are within 5%. Third, the reduced scattering coefficient of Intralipid 10% and Intralipid 30% can be scaled from that of Intralipid 20% with an error of 9% and 2%, respectively. A similar scaling property is valid for Lipovenoes and Lipofundin S. We have verified that this scaling property depends on the composition of the fat emulsions: If the ingredients exactly scale with the concentration then the reduced scattering coefficient almost exactly scale as well.
Tipologia CRIS:
01.01 Articolo in rivista
Keywords:
optica; tissue optics; optical properties
Elenco autori:
Mercatelli, Luca; Sani, Elisa
Autori di Ateneo:
MERCATELLI LUCA
SANI ELISA
Link alla scheda completa:
https://iris.cnr.it/handle/20.500.14243/241044
Pubblicato in:
APPLIED OPTICS (2004)
Journal
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