Production of octadienal in the marine diatom Skeletonema costatum

Marine diatoms produce a,b,g,d-unsaturated aldehydes that have detrimental effects on the reproduction of their natural predators. The production of these defensive metabolites is suggested to involve enzymatic oxidation of polyunsaturated fatty acids. In this paper, feeding experiments with labelled precursor provide clear evidence in support of the origin of octadienals ( from 6,9,12-hexadecatrienoic acid, thus proving the involvement of novel lipoxygenase/lyase activity for the oxidation of C16 fatty acids.