Publication Date:
2014
abstract:
Anderson-Fabry disease (AFD) is a rare, X-linked, genetic disorder
caused by mutations in the gene encoding the lysosomal enzyme ?galactosidase A and characterized by the progressive accumulation of
glycosphingolipids, particularly globotriaosylceramide (Gb3) in the vascular endothelium and in different tissues. Impairment in coronary
vasodilator capacity has previously been demonstrated in patients
with AFD, using positron emission tomography (PET) and dipyridamole
Iris type:
01.01 Articolo in rivista
Keywords:
Anderson-Fabry disease; Cold pressor test; Coronary flow reserve; Dipyridamole; Echocardiography; Endothelium
List of contributors:
Riccio, Eleonora
Published in: