Lipase catalysed resolution of ferrocene cyanohydrin: Access to novel ferrocenyl aminoalcohoIs and diamines

Academic Article
Publication Date:
1997
abstract:
R)-(+)-Ferrocene cyanohydrin acetate, obtained by enzymatic acylation of ferrocene cyanohydrin, may be transformed by reduction and alkylation into novel ferrocenyl ?-aminoalcohoIs. Substitution of acetate by methanolic HNMe2 proceeds with racemisation, but significant diastereoselection is observed on Strecker reaction using (-)PhCH(Me)NHMe
Iris type:
01.01 Articolo in rivista
List of contributors:
Authors of the University:
Handle:
https://iris.cnr.it/handle/20.500.14243/201492
Published in:
TETRAHEDRON-ASYMMETRY
Journal