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TITAN Project: microfluidic and sensing tools for immunotherapy

Abstract
Publication Date:
2023
abstract:
Titan project aims to improve immunotherapy, targeting the efficiency of methods to obtain genetically engineered T cells. Immunotherapy has achieved great success in clinical trials, but it is currently very expensive in terms of time required for analysis, reagents and samples. TITAN aims to the continuous sampling of critical quality attributes, in order to quickly recognize deviations from the desired range and take appropriated corrective actions of process parameters, for an optimal outcome. To achieve its aims, TITAN is currently developing microfluidic and sensing tools for the accurate and efficient real-time monitoring of the T-cells amplification process.
Iris type:
04.02 Abstract in Atti di convegno
Keywords:
: CAR-T cell immunotherapy; on-chip quality control; microfluidic and sensing platform
List of contributors:
Siciliano, Giulia; Garzarelli, Valeria; Mohammed, AHMED ALSADIG AHMED; Foscarini, Alessia; Gigli, Giuseppe; Chiriaco', MARIA SERENA; Turco, Antonio; Ferrara, Francesco; Stampone, Benedetta; Trotta, Gianluca; Primiceri, Elisabetta; DE TULLIO, MARCO DONATO
Authors of the University:
CHIRIACO' MARIA SERENA
FERRARA FRANCESCO
PRIMICERI ELISABETTA
TROTTA GIANLUCA
TURCO ANTONIO
Handle:
https://iris.cnr.it/handle/20.500.14243/439676
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