Direct Synthesis of ESBO Derivatives-O-18 Labelled with Dioxirane

This work addresses a new approach developed in our laboratory, consisting in the application of isolated dimethyldioxirane (DDO, 1a) labelled with O-18 for synthesis of epoxidized glyceryl linoleate (Gly-LLL, 2). We expect that this work could contribute in improving analytical methods for the determination of epoxidized soybean oil (ESBO) in complex food matrices by adopting an O-18-labelled-epoxidized triacylglycerol as an internal standard.