VITAMIN D STATUS MAY CONTRIBUTE TO SERUM IGF1 CONCENTRATIONS IN HEALTHY SUBJECTS

Objective The aim of the study was to evaluate whether vitamin D [25-(OH) D3] status affects serum IGF1 concentrations in healthy subjects. Design and Patients Two hundred and forty one consecutive healthy subjects were included in the present study. Measurements Serum IGF1 and 25-(OH) D3 concentrations. Results As expected, serum IGF1 concentrations progressively decreased with age (r=-0.55, p0.0001); on the contrary, gender was not related to serum IGF1 levels. A positive relationship was identified between serum 25-(OH) D3 and IGF1 concentrations (r