Bicyclo[2.2.2]octane analogues of patchouli alcohol by Sakurai reaction and Nagata cyclization. Synthesis and olfactory properties of novel isopropyl derivatives

Academic Article
Publication Date:
2008
abstract:
The synthesis of bicyclo[2.2.2]octane patchouli alcohol analogues by the Sakurai conjugate addition and Nagata cyclization is described. By this approach, complementary to those so far adopted and based on the Diels-Alder addition, known analogues 2, 3 and 20 and new analogues 8-11, with 1-isopropylbicyclo[2.2.2]octane structure, could be obtained. The olfactory properties of 8 and 10 were also evaluated. ©ARKAT USA, Inc.
Iris type:
01.01 Articolo in rivista
Keywords:
1-isopropylbicyclo[2.2.2]octane derivatives; Nagata cyclization; Olfactory properties; patchouli alcohol analogues; Sakurai allylation; Synthesis
List of contributors:
Authors of the University:
Handle:
https://iris.cnr.it/handle/20.500.14243/321952
Published in:
ARKIVOC (PRINT)
Journal