Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons

Academic Article

Publication Date:

2019

abstract:

Fossati et al. show that, in stark contrast to other iGluRs, the glutamate receptor delta-1 (GluD1) operates at inhibitory, rather than excitatory, synapses in the cortex. GluD1 mediates trans-synaptic signaling governing the formation of synapses between specific interneurons and pyramidal neurons.

Iris type:

01.01 Articolo in rivista

Keywords:

adhesion molecule; cerebellin; cortical circuits; gephyrin; glutamate receptor delta-1; inhibitory synapse; synapse specificity; synaptic signaling; synaptogenesis; trans-synaptic interaction

List of contributors:

Fossati, Matteo

Authors of the University:

FOSSATI MATTEO

Handle:

https://iris.cnr.it/handle/20.500.14243/410681

Published in:

NEURON (CAMB. MASS.)

Journal

Overview

URL

https://www.sciencedirect.com/science/article/pii/S0896627319308013

Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons

Fossati, Matteo

NEURON (CAMB. MASS.)

Overview

URL