NGF/anti-VEGF combined exposure protects RCS retinal cells and photoreceptors that underwent a local worsening of inflammation
Academic Article
Publication Date:
2017
abstract:
Our previous study highlighted the potential nerve growth factor (NGF) effect on damaged photoreceptors from a rat model of spontaneous Retinitis Pigmentosa (RP). Herein, we tested the combined NGF/anti-vascular endothelial growth factor (alpha VEGF) effect on cultured retinal cells isolated from Royal College of Surgeons (RCS) rats receiving an intravitreal VEGF injection (iv-VEGF) to exacerbate retinal inflammation/neovascularization.
Iris type:
01.01 Articolo in rivista
Keywords:
NGF; Anti-VEGF; Retinitis pigmentosa; Neuroprotection; Retinal degeneration; Apoptosis
List of contributors:
Aloe, Luigi; Petrella, Carla
Published in: