Exogenous and endogenous cannabimimetic metabolites

Only a few discoveries in the fields of pharmacology and physiology have benefited from the work of organic and synthetic chemists like the identification of the existence and possible physiological function of the 'endogenous cannabinoid system'. The review emphatizes the key role played by chemists in this area of pharmacological researh, and highlights the possible industrial implications of the discovery of cannabimimetic metabolites and of their mechanism of action.