Temporal information coding properties of a network of inhibitory interneurons

Inhibitory interneurons are coupled by electrical and inhibitory synapses and exert a powerful control of the discharges of principal cells. In this paper, the transmission properties of excitatory synaptic inputs by a network of interneurons, are studied by using a computational approach. It is shown that both the rise and decay time constants, describing the time course of the excitatory synaptic inputs, have a strong effect on the output jitter of the fired spikes. Similar results were found by changing the values of the other parameters describing the network. Lastly, it is shown that the presence of the electrical coupling between interneurons confers to the network the capability of transmitting, with less temporal spread, the timing information contained in its inputs.