Ceric ammonium nitrate/pyridine: A mild reagent for the selective deprotection of cyclic Acetals and ketals in the presence of acid labile protecting groups
Academic Article
Publication Date:
2002
abstract:
The reagent system ceric ammonium nitrate/pyridine can perform the cleavage of primary and (in some cases) secondary acetonides, benzylidenes and tetrahydropyranyl ethers. The mild acididity of the reaction system (pH 4.4) allows deprotections to be performed in the presence of several acid labile protecting groups.
Iris type:
01.01 Articolo in rivista
Keywords:
ceric ammonium nitrate; lanthanides; hydroxyl-protecting groups; hydrolysis; carbohydrates
List of contributors:
Manzo, Emiliano
Published in: