In vitro biocompatibility of titanium oxide for prosthetic devices nanostructured by metal-organic chemical vapour deposition

Metal-Organic Chemical Vapour Deposition (MOCVD) has recently been proposed as a technique to coat orthopaedic and dental prostheses with metal nanostructured oxide films either through the decomposition of oxygenated compounds (single-source precursors) or the reaction of oxygen-free metal compounds with oxygenating agents. The present study was performed to assess the in vitro biocompatibility in terms of cellular proliferation and activation of commercially pure Ti (control material: TI/MA) implants coated with nanostructured TiO2 film by MOCVD (Ti/MOCVD) using osteoblasts like cells cultures (MG-63) In conclusion, the current findings demonstrate that the nanostructured TiO2 coating positively affects the osteoblasts like cells.