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Diastereoselective synthesis of beta-hydroxy sulfoxides: Enzymatic and biomimetic approaches

Academic Article
Publication Date:
2007
abstract:
Stereoselectivities of up to 98 % have been found in the enzymatic synthesis of ?-hydroxy sulfoxides catalyzed by cyclohexanone monooxygenase (CHMO). The diastereoselectivity of the "one-pot" preparation of the title compounds in the presence of bovine serum albumin has also been investigated
Iris type:
01.01 Articolo in rivista
Keywords:
Sulfoxides; Cyclohexanone monooxygenase; Kinetic resolution; Bovine serum albumin; Enzyme catalysis
List of contributors:
Zambianchi, Francesca; Ottolina, Gianluca
Authors of the University:
OTTOLINA GIANLUCA
ZAMBIANCHI FRANCESCA
Handle:
https://iris.cnr.it/handle/20.500.14243/167499
Published in:
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (PRINT)
Journal
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URL

http://onlinelibrary.wiley.com/doi/10.1002/ejoc.200600624/abstract
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