Synthetic studies on natural diterpenoid glyceryl esters

Synthesis of natural bicyclic and tricyclic diterpenoid diacylglycerols has been performed by regioselective coupling of terpenoid acid with glycerol at 1'-sn position. This method may be considered a general approach to obtain optically active acylglycerols. The preparation of C-13-labelled geranylgeranoic acid glyceryl esters is also described here. (C) 2000 Elsevier Science Ltd. All rights reserved.