Composites for bone tissue engineering based on antibacterial mesoporous bioactive glassy oxides

In the field of tissue engineering, the development of biomaterials with enhanced properties results a great challenge. In designing multifunctional substrates for tissue engineering, many strategies been reported to improve the performances of polymer-based composite materials. As reported in the literature, silver-containing mesoporous bioactive glasses (Ag-MBGs) were properly synthesized and analysed. The aim of the present study was to develop composite substrates consisting of a poly(?-caprolactone) (PCL) matrix and Ag-MBGs with improved antibacterial properties. Preliminary structural/functional and biological analyses allowed to evaluate the effect of Ag-MBGs embedded in the polymer matrix.