Circulating extracellular vesicles as non-invasive biomarker of rejection in heart transplant
Academic Article
Publication Date:
2020
abstract:
BACKGROUND: Circulating extracellular vesicles (EVs) are raising considerable interest as a non-invasive diagnostic tool, as they are easily detectable in biologic fluids and contain a specific set of nucleic acids, proteins, and lipids reflecting pathophysiologic conditions. We aimed to investigate differences in plasma-derived EV surface protein profiles as a biomarker to be used in combination with endomyocardial biopsies (EMBs) for the diagnosis of allograft rejection.
Iris type:
01.01 Articolo in rivista
Keywords:
extracellular vesicles; allograft rejection; heart transplant; biomarker; machine learning
List of contributors:
DI SILVESTRE, Dario
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