Lattice Boltzmann method as a computational framework for multiscale haemodynamics

Recent developments of the lattice Boltzmann method for large-scale haemodynamic applications are presented, with special focus on multiscale aspects, including the self-consistent dynamics of suspended biological bodies and their coupling to surface structures, such as the glycocalyx, in the proximity of endothelium using unstructured grids. The description of such multiscale phenomena, each one treated with a suitable variation of the lattice Boltzmann method, opens up new perspectives for a fundamental understanding of the physical mechanisms underlying cardiovascular pathologies, such as plaque growth and the subsequent development of atherosclerotic diseases.