A facile one-pot synthesis of 8-oxo-7,8-dehydro-(2 -deoxy)adenosine in water

Academic Article
Publication Date:
2006
abstract:
Reaction of 2-mercaptoethanol with 8-bromo-2-deoxyadenosine and 8-bromo-adenosine in aqueous solution and in the presence of triethylamine gave the 8-oxo-adenine derivatives in very good yields. Some mechanistic details are reported.
Iris type:
01.01 Articolo in rivista
Keywords:
DNA damage; Nucleosides; 8-Oxo-78-dihydro-2-deoxyadenosine; Mercaptoethanol; 8-Bromo-2 -deoxyadenosine
List of contributors:
Authors of the University:
Handle:
https://iris.cnr.it/handle/20.500.14243/36313
Published in:
TETRAHEDRON LETTERS
Journal