Enhancing the effectiveness of nucleoside analogs with mTORC1 blockers to treat acute myeloid leukemia patients

Academic Article
Publication Date:
2013
abstract:
Comment on A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemia. [Oncotarget. 2012]
Iris type:
01.01 Articolo in rivista
Keywords:
targeted therapy; combination therapy; leukemia initiating cells; PI3K; Akt; mTOR; cell cycle; apoptosis; autophagy; translation
List of contributors:
Authors of the University:
Handle:
https://iris.cnr.it/handle/20.500.14243/270588
Published in:
CELL CYCLE (GEORGET. TEX.)
Journal