Memory of chirality approach to the enantiodivergent synthesis of chiral benzo[ d ]sultams

The "memory of chirality" stereodivergent synthesis of polyfluorobenzo[d]sultams has been developed. The interest of this protocol resides in the possibility of using the chirality of a starting sulfonamide single enantiomer to synthesize the target sultams in both absolute configurations, by using different base systems, under homogeneous conditions. © 2013 American Chemical Society.