Publication Date:
2018
abstract:
Multidefence antioxidants represent a valuable solution for the protection against oxidative stress. From the planned synthesis of a catechol-tocopherol hybrid, we isolated a catechol-hydroquinone hybrid through a BBr3-mediated benzochromene-fluoren-1-ol transposition. The compound prepared showed a remarkable chain-breaking antioxidant in the catechol portion, while the very sensitive hydroquinone moiety revealed to be an efficient generator of hydroperoxyl radicals.
Iris type:
01.01 Articolo in rivista
Keywords:
chain-breaking activity; hydroxyl radical; multidefence antioxidants; polyphenols; transposition
List of contributors:
Baschieri, Andrea
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