Catalytic, asymmetric synthesis of cyanohydrin esters: The effect of anhydride structure on enantioselectivity
Academic Article
Publication Date:
2004
abstract:
A bimetallic titanium(salen) complex has been shown to catalyse the asymmetric addition of potassium cyanide to aldehydes in the presence of a range of anhydrides. leading to cyanohydrin esters. Linear aliphatic anhydrides (acetic and propionic) gave products with higher enantiomeric purity than those obtained using pivalic or benzoic anhydrides.
Iris type:
01.01 Articolo in rivista
Keywords:
cyanohydrin; catalyst; asymmetric; ester; titanium; salen
List of contributors:
Carta, Paola
Published in: