Microenvironmental Rigidity of 3D Scaffolds and Influence on Glioblastoma Cells: A Biomaterial Design Perspective

Glioblastoma (GBM), or grade IV glioma, is an extremely aggressive tumor that infiltrates through the brain leaving the patient with a median survival time from 12 to 15 months. Here we report a brief opinion on the current work on the how cell behavior is influenced by matrix stiffness