Immunogenic properties of a chimeric plant virus expressing a hepatitis C virus (HCV)-derived epitope: New prospects for an HCV vaccine
Academic Article
Publication Date:
2005
abstract:
ABSTRACT:A vaccine against Hepatitis C Virus (HCV) is urgently needed due to the unsatisfactory clinical respone to current therapies. We evaluated the immunological properties of a chimeric Cucumber mosaic virus (CMV), a plant virus engineered to express on its surface a synthetic peptide derived from many HVR1 sequences of the HCV envelope protein E2 (R9 mimotope).
Iris type:
01.01 Articolo in rivista
Keywords:
HCV vaccine; T lymphocytes; cytokines; CMV; plant viruses
List of contributors:
DE STRADIS, Angelo; Boscia, Donato
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