SIR2002: the program

The structure solution of small molecules is, nowdays, almost a routine process; the ab initio structure solution of macromolecules is, on the country, a challenge for anu crystallographic software. Four programs are well documented: Shake-and-bake (Weeks et al.,1994), SHELX-D (Sheldrick, 1998), ACORN (Foadi et al., 2000) and SIR2000-N (Burla el al.,2001). A new direct-methods program, SIR2002 (Burla et al.,2002), has been designed to solve both small and large crystal structures.