Publication Date:
2012
abstract:
Despite the role of chloride channels and anion/proton antiporters of the CLC protein family in physiological processes and different genetic diseases, their pharmacology has been under-developed. In this issue of Chemistry & Biology, Howery et al. report the synthesis of 4?-octanamidostilbene-2,2?-disulfonate, the first high-affinity inhibitor of a CLC antiporter, a critical step toward reviving the CLC pharmacology.
Iris type:
01.01 Articolo in rivista
List of contributors:
Pusch, Michael; Zifarelli, Giovanni
Published in: