New synthesis of PNA-3? DNA linker monomers, useful building blocks to obtain PNA/DNA chimeras

A new synthetic strategy to get the PNA-3? DNA linker with the monomethoxytrityl (Mmt)
group as temporary protection of the backbone to be used for the synthesis of PNA/DNA
chimeras was employed and a convenient strategy to obtain Mmt PNA monomers was
developed. The synthetic strategies take advantage of the introduction of the acid-labile Mmt-
protecting group in the first step.