Conformational preferences of chiral molecules: free-jet rotational spectrum of 1-(4-fluorophenyl)-1-ethanol

The rotational spectra of normal and O-d species of the most stable conformer of chiral 1-(4-fluorophenyl)-1-ethanol have been measured by free-jet absorption millimeter-wave spectroscopy. The observed species is stabilized by an O-H-pi interaction and it is at least 1 kcal mol(-1) more stable than the remaining conformers.